GCA Polyclonal Antibody-BS8700

GCA Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8700-50, BS8700-100

Swiss-Prot: P28676

Host: Rabbit

GCA Polyclonal Antibody-BS8700

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GCA polyclonal antibody detects endogenous levels of GCA protein.

Bioworld Molecular Weight: ~ 24kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using GCA antibody., Immunofluorescence analysis of A549 cell using GCA antibody.

Alternative Name: Grancalcin; GCA; GCL

Immunogen: Recombinant full length Human GCA.

Modification: Unmodified

Conjugate: Unconjugated