GCAT Polyclonal Antibody - E-AB-18831

GCAT Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18831-60, E-AB-18831-120, E-AB-18831-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GCAT

Target Synonym: 2 amino 3 ketobutyrate CoA ligase ; 2 amino 3 ketobutyrate coenzyme A ligase; mitochondrial; 2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Aminoacetone synthase; GCAT; Glycine acetyltransferase; glycine C acetyltransferase ; glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase); KBL; KLB; mitochondrial

Research Areas: Cancer, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O75600

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human GCAT

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Calculated MW: 45 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only