Product Description

GCG Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6040-50, BS6040-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01275

Host: Rabbit

Reactivity: Human

Applications: IHC,IF

All Applications: IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GCG polyclonal antibody detects endogenous levels of pro-glucagon protein.

Bioworld Molecular Weight: 0

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry of paraffin-embedded human colon carcinoma using GCG antibody at dilution of 1:100 (40x lens).

Alternative Name: Glucagon; GCG; Glucagon precursor. GRPP.

Immunogen: Recombinant full length Human GCG.

Conjugate: Unconjugated

Modification: Unmodified