GCH1 Polyclonal Antibody - RA32432

GCH1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32432-50, RA32432-100

Citations, Manuals and MSDS Available upon request.

Background: GTP cyclohydrolase 1 (GCH1) Homo sapiens This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2643

Protein MW (KDa): 27

SWISS: P30793

Source: Rabbit

Research Use Only