Product Description

GCK/GLK Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25257-50, RA25257-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein) Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)

Clonality: Polyclonal

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 100

Protein Molecular Weight (kDa): 100

Storage: -20°C/1 year

Human Gene ID: 5871/8491

Human SwissProt Number: Q12851/Q8IVH8

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only