GCN2 (phospho Thr899) rabbit pAb - ES6270

GCN2 (phospho Thr899) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6270-50, ES6270-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014],

Alternate Name: EIF2AK4; GCN2; KIAA1338; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human GCN2 around the phosphorylation site of Thr899. AA range:865-914

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 440275

Human SWISS Prot NO: Q9P2K8

Subcellular Location: Cytoplasm

Research Use Only