Product Description

GCNT1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65721-50, BS65721-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regμlates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregμlation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep

Host: Rabbit

Applications: WB

Alternate Names: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, C2GNT, C2GNT L, C2GNT1, C2GnTL, Core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2 GlcNAc transferase, Core2-GlcNAc-transferase, GCNT 1, GCNT 1, GCNT1, GCNT1_HUMAN, glucosaminyl (N-acetyl) transferase 1 core 2, NACGT2.   

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from Human GCNT1:201-260/428

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: GCNT1 Polyclonal Antibody detects endogenous levels of GCNT1 protein.

Molecular Weight: 52 kD，50 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q02742

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only