Product Description

GCNT1 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65721-50, BS65721-100

Swiss-Prot: Q02742

Host: Rabbit

GCNT1 Polyclonal Antibody-BS65721

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Cow, Sheep,

Applications: WB,

All Applications: WB=1:500-2000

Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

Purification and Purity: affinity purified by Protein A

Specificity: GCNT1 Polyclonal Antibody detects endogenous levels of GCNT1 protein.

Bioworld Molecular Weight: 52 kD，50 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- GCNT1 at 1/1000 dilution, Primary: Anti- GCNT1 at 1/1000 dilution

Alternative Name: 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase; Beta-1; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; C2GNT; C2GNT L; C2GNT1; C2GnTL; Core 2 branching enzyme; Core 2 GNT; Core 2-branching enzyme; Core2 GlcNAc transferase; Core2-GlcNAc-transferase; GCNT 1; GCNT 1; GCNT1; GCNT1_HUMAN; glucosaminyl (N-acetyl) transferase 1 core 2; NACGT2.   

Immunogen: KLH conjugated synthetic peptide derived from Human GCNT1:201-260/428

Modification: Unmodified

Conjugate: Unconjugated