Product Description

GCP5 (I779) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3303-50, BS3303-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The γ-Tubμlin complex is composed of γ Tubμlin and the γ-Tubμlin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubμle organizing centers. γ-Tubμlin complex components are localized to both the centrosome, where they are involved in microtubμle nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubμlin complex. GCP5 (γ-Tubμlin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the γ-Tubμlin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compμlsive behavior and lower intellectual ability.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: Gamma-tubμlin complex component 5, GCP-5, TUBGCP5, GCP5, KIAA1899

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 746-794 of Human GCP5.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GCP5 (I779) polyclonal antibody detects endogenous levels of GCP5 protein.

Molecular Weight: ~ 118 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96RT8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only