GCS-Alpha-1 Polyclonal Antibody - BT-AP03524

GCS-Alpha-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03524-20, BT-AP03524-50, BT-AP03524-100

Citations, Manuals and MSDS Available upon request.

Background: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. Guanylate cyclase soluble subunit alpha-3 encoded by GUCY1A3 is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Research Areas: Signal Transduction

Target Protein: GUCY1A3

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GCS-alpha-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 77452

UniProt Accession: Human: Q02108; Mouse: Q9ERL9; Rat: P19686

Synonyms: GUCY1A3; GUC1A3; GUCSA3; GUCY1A1; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit

GeneID: Human: 2982; Mouse: 60596

Research Use Only