GDF-3 rabbit pAb - ES4373

GDF-3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4373-50, ES4373-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

Alternate Name: GDF3; Growth/differentiation factor 3; GDF-3

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 41kD

Human Gene ID: 9573

Human SWISS Prot NO: Q9NR23

Subcellular Location: Secreted. Cytoplasm. Mainly accumulated in the cytoplasm.

Research Use Only