GDF-6 Polyclonal Antibody - RA25283

GDF-6 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25283-50, RA25283-100

Citations, Manuals and MSDS Available upon request.

Background: growth differentiation factor 6 (GDF6) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 392255

Protein MW (KDa): 50

SWISS: Q6KF10

Source: Rabbit

Research Use Only