GDF-7 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA25285-50, RA25285-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: growth differentiation factor 7 (GDF7) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: GDF7, Growth/differentiation factor 7, GDF-7 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 47 Protein Molecular Weight (kDa): 47 Storage: -20°C/1 year Human Gene ID: 151449 Human SwissProt Number: Q7Z4P5 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only