Product Description

GDF-8 (L38) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2852-50, BS2852-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O14793

Host: Rabbit

Reactivity: Human, Mouse

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Myostatin (GDF8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 113 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor ß superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of GDF-8 (L38) pAb in paraffin-embedded human colorectal cancer carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 43 kDa

Specificity: GDF-8 (L38) polyclonal antibody detects endogenous levels of GDF-8 protein.

Alternative Name: GDF8; MSTN; Myostatin; GDF-8; Growth/differentiation factor 8

Immunogen: Synthetic peptide, corresponding to amino acids 11-60 of Human GDF-8.

Conjugate: Unconjugated

Modification: Unmodified