GDF-8 rabbit pAb - ES5504

GDF-8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5504-50, ES5504-100

Citations, Manuals and MSDS Available upon request.

Background: myostatin (MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],

Alternate Name: MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human GDF-8. AA range:38-87

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 2660

Human SWISS Prot NO: O14793

Subcellular Location: Secreted

Research Use Only