Product Description

GDF11 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66744-50, MB66744-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GDF-11, a member of the transforming growth factor β (TGFβ) superfamily, controls anterior/posterior patterning of the axial skeleton, regμlates organogenesis by controlling expression of GDNF, contributes to the control of Hox gene expression and induces phosphorylation of Smad2. In addition, GDF-11 mediates signaling of Nodal during left-right patterning and development of head structures and inhibits generation of new neurons by neuronal progenitors in the olfactory epithelium.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: BMP11, Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human GDF11. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of GDF11 protein.

Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95390

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only