Product Description

GDI1 Polyclonal Antibody

Catalogue Numbers: BS5731-50, BS5731-100

Sizes: 50µl, 100µl

Alternative Name: Rab GDP dissociation inhibitor alpha; Rab GDI alpha; Rab GDI α; Rab GDIα; RabGDIα; Guanosine diphosphate dissociation inhibitor 1; GDI-1; Oligophrenin-2; Protein XAP-4; GDIL; OPHN2; RABGDIA; XAP4

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P31150

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI α (also known as XAP-4) and Rab GDI β. While the mammalian Rab GDI β-genes are ubiquitously expressed, the Rab GDI α genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI α may serve a specific function in neural signalmtransmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GDI1 polyclonal antibody detects endogenous levels of GDI1 protein.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of GDI1 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate

Immunogen: Synthetic peptide, corresponding to amino acids 402-447 of Human GDI1.

Conjugate: Unconjugated

Modification: Unmodified