Product Description

GDNF Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65644-50, BS65644-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Neurobiology. Neurotrophins. Neuroscience. This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in cμlture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

Host: Rabbit

Applications: IHC-P

Alternate Names: glial cell line derived neurotrophic factor, Astrocyte derived trophic factor 1, Astrocyte derived trophic factor, ATF 1, ATF 2, ATF1, ATF2, Glial cell derived neurotrophic factor, Glial derived neurotrophic factor, HFB1 GDNF, GDNF_HUMAN, Atf, gdnf, Glial Cell Line Derived Neurotrophic Factor, Glial cell line-derived neurotrophic factor, Glial derived neurotrophic factor, hGDNF, HSCR3.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human GDNF

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: GDNF Polyclonal Antibody detects endogenous levels of GDNF protein.

Molecular Weight: 1kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P39905

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only