GDPD3 Polyclonal Antibody Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Sizes: 50µl, 100µl Catalogue Numbers: BS65451-50, BS65451-100 Swiss-Prot: Q7L5L3 Host: Rabbit GDPD3 Polyclonal Antibody-BS65451 Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Reactivity: Human, Mouse, Rat, Dog, Horse, Applications: IHC-P All Applications: IHC-P=1:100-500 Background: GDE3, also known as glycerophosphodiester phosphodiesterase 3, glycerophosphodiester phosphodiesterase domain containing 2 (GDPD2) or osteoblast differentiation promoting factor (OBDPF), is a 539 amino acid protein belonging to the glycerophosphoryl diester phosphodiesterase family. Possessing glycerophosphoinositol inositolphosphodiesterase activity, GDE3 hydrolyzes glycerophosphoinositol to form inositol 1-phosphate and glycerol, and is suggested to play a role in Actin cytoskeleton remodeling and osteoblast differentiation and growth. A multi-pass membrane protein, GDE3 localizes to cell membrane and cytoplasm, and colocalizes with actin in the cytoskeleton. GDE3 contains one GDPD domain, binds calcium as a cofactor and is encoded by a gene mapping to human chromosome Xq13.1. Purification and Purity: affinity purified by Protein A Specificity: GDPD3 Polyclonal Antibody detects endogenous levels of GDPD3 protein. Bioworld Molecular Weight: 37kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GDPD3) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C., Paraformaldehyde-fixed, paraffin embedded (Human brain glioma)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GDPD3) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C. Alternative Name: FLJ22603; GDPD 3; GDPD3; GDPD3_HUMAN; Glycerophosphodiester phosphodiesterase domain containing 3; Glycerophosphodiester phosphodiesterase domain-containing protein 3; MGC4171. Immunogen: KLH conjugated synthetic peptide derived from human GDPD3:101-200/318 Modification: Unmodified Conjugate: Unconjugated