GEN rabbit pAb - ES16215

GEN rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16215-50, ES16215-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human GEN AA range: 61-111

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 348654

Human SWISS Prot NO: Q17RS7

Subcellular Location: Nucleus

Research Use Only