Product Description

Gephyrin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90573-50, BS90573-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NQX3(Human) Q03555(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200

Background: The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Gephyrin polyclonal antibody detects endogenous levels of Gephyrin protein.

Bioworld Molecular Weight: 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Gephyrin on SK-Br-3 cell (1) and rat kidney tissue (2) lysate using anti-Gephyrin antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Gephyrin antibody. Counter stained with hematoxylin. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6) for 20 mins.

Alternative Name: MPT adenylyltransferase, MPT Mo-transferase, GPHN, GPH, KIAA1385, Domain E, Domain G, GEPH, GEPH, GPH, GPHN, GPHRYN, KIAA1385, Molybdopterin molybdenumtransferase, MPT adenylyltransferase, MPT Mo-transferase,

Conjugate: Unconjugated

Modification: Unmodified