Gfi-1 Monoclonal Antibody - RA11293

Gfi-1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11293-50, RA11293-100

Citations, Manuals and MSDS Available upon request.

Background: growth factor independent 1 transcriptional repressor (GFI1) Homo sapiens This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 2672

SWISS: Q99684

Source: Mouse

Research Use Only