Product Description

GFM2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62364-50, BS62364-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mitochondrial translation is critical for maintaining function and preventing impairment of mitochondrial DNA, with mitochondrial translation elongation factors playing an essential role in this process. EF-G2 (elongation factor G2), also known as RRF2mt (ribosome-releasing factor 2, mitochondrial), GFM2 or MSTP027, is a 779 amino acid protein belonging to the GTP-binding elongation factor family and EF-G/EF-2 subfamily. Localizing to mitochondrion, EF-G2 is widely expressed with high levels found in adμlt heart, skeletal muscle and kidney as well as adμlt and fetal liver. EF-G2 mediates ribosome recycling and by interacting directly with MRRF on the ribosome large subunit, is required for ribosome dissociation from mRNA. Existing as five alternatively spliced isoforms, the gene encoding EF-G2 maps to human chromosome 5q13.3.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2, Elongation factor G2, hEFG2, GFM2, EFG2, MSTP027

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human GFM2.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GFM2 polyclonal antibody detects endogenous levels of GFM2 protein.

Molecular Weight: ~ 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q969S9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only