Product Description

GFRA2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53256-60, E-AB-53256-120, E-AB-53256-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GFRA2

Target Synonym: GDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF receptor alpha-2; GDNF receptor beta; GDNFR beta; GDNFR-alpha-2; GDNFR-beta; GDNFRB; GFR alpha 2; GFR-alpha-2; GFRA 2; Gfra2; GFRA2; Glial cell line derived neurotrophic factor family receptor alpha2b; Glial cell line derived neurotrophic factor receptor beta; Neurturin receptor alpha; NRTNR alpha; NRTNR-alpha; NTNR alpha; NTNR-alpha; NTNRA; PI linked cell surface accessory protein; PI linked cell-surface accessory protein; RET ligand 2; RETL 2; RETL2; TGF beta related neurotrophic factor receptor 2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor GPI anchored; TRNR 2; TRNR2

Research Areas: Cancer, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O00451

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human GFRA2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:1000-1:2000

Calculated MW: 52 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only