GFRA2 Rabbit pAb - A2954

GFRA2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A2954-20, A2954-100

Citations, Manuals and MSDS Available upon request.

Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 52kDa

Observed Molecular Weight: 34kDa/55kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 2675

SWISS: O00451

Alternate Names: NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; GFRA2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:200 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Neuroscience.

NCBI Alias: GFRA2

Research Use Only