Product Description

GGPS1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: AP6016-50, AP6016-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GGPS1 (geranylgeranyl diphosphate synthase 1), also known as GGPPS, GGPPSase (geranylgeranyl pyrophosphate synthetase) or GGPPS1, is a member of the FPP/GGPP synthetase family of trans-prenyltransferases. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate (GGPP), a precursor of geranylgeranylated proteins and carotenoids. GGPP is a major isoprenoid responsible for the C20-prenylation of proteins and the regμlation of the nuclear hormone receptor LXRå. More specifically, GGPS1 functions as an oligomeric molecμle and mediates the condensation of farnesyl diphosphate (FPP) with isopentenyl diphosphate to yield GGPP. GGPS1 contains five amino acid motifs that are conserved in trans-prenyltransferases and three potential N-glycosylation sites.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fragment corresponding to a region within amino acids 1-295 of Human GGPS1.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GGPS1 polyclonal antibody detects endogenous levels of GGPS1 protein.

Molecular Weight: ~ 35 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95749

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only