Product Description

GGT5 Polyclonal Antibody

Catalogue Numbers: BS60688-50, BS60688-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P36269

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4; it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GGT5 polyclonal antibody detects endogenous levels of GGT5 protein.

Extra Notes: Western blot (WB) analysis of GGT5 pAb at 1:500 dilution
Lane1:H460 whole cell lysate(40ug)
Lane2:LO2 whole cell lysate(40ug)
Lane3:The renal tissue lysate of Mouse(40ug)
Lane4:MCF-7 whole cell lysate(40ug)
Lane5:HUT78 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 68 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Gamma-glutamyltransferase 5; GGT 5; Gamma-glutamyl transpeptidase-related enzyme; GGT-rel; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Glutathione hydrolase 5; Leukotriene-C4 hydrolase; GGT5; GGTLA1

Immunogen: A synthetic peptide corresponding to residues in Human GGT5

Conjugate: Unconjugated

Modification: Unmodified