GH1 Polyclonal Antibody - E-AB-92796

GH1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92796-60, E-AB-92796-120, E-AB-92796-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GH1

Target Synonym: GH1; GH; GH-N; GHB5; GHN; IGHD1B; hGH-N

Research Areas: Cancer, Developmental Biology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P01241

Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human GH1

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200, IF 1:50-1:200

Calculated MW: 19kDa/20kDa/22kDa/24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only