GH1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7675-20, A7675-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Category: Polyclonal Antibodies
Applications: WB, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 25kDa
Observed Molecular Weight: 23kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 2688
SWISS: P01241
Alternate Names: GH; GHN; GH-N; GHB5; IGHD2; hGH-N; IGHD1A; IGHD1B; GH1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, Cytokines, NF-kB Signaling Pathway, Stem Cells.
NCBI Alias: GH1
Research Use Only