Product Description

GHR Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17322-60, E-AB-17322-120, E-AB-17322-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GHR

Target Synonym: GH receptor; GH-binding protein; GHBP; GHBP; included; GHR; GHR; Growth hormone binding protein; Growth hormone receptor; Growth hormone receptor precursor; Growth hormone-binding protein; Growth hormone-binding protein; included; Increased responsiveness to growth hormone; included; Serum binding protein; Serum-binding protein; Somatotropin receptor

Research Areas: Cancer, Cell biology, Developmental biology, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P10912

Background: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human GHR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-2000, ELISA 1:2000-5000

Calculated MW: 72 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only