Product Description

GIT2 (phospho-Tyr392) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25327-50, RA25327-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GIT ArfGAP 2 (GIT2) Homo sapiens This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB

Alternate Names: ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

Clonality: Polyclonal

Dilution: WB 1:1000-2000

Molecular Weight: 84

Protein Molecular Weight (kDa): 84

Storage: -20°C/1 year

Human Gene ID: 9815

Human SwissProt Number: Q14161

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only