GLA Polyclonal Antibody - E-AB-67013

GLA Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67013-60, E-AB-67013-120, E-AB-67013-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GLA

Target Synonym: GLA; GALA

Research Areas: Cancer,Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P06280

Background: This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human GLA

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:50-1:100

Calculated MW: 48kDa

Observed MW: 49kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only