
GLB1L3 Polyclonal Antibody
Catalogue Numbers: BS61145-50, BS61145-100
Sizes: 50µl, 100µl
Alternative Name: Beta-galactosidase-1-like protein 3 (EC:3.2.1.-); GLB1L3
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8NCI6
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: GLB1L3 (beta-galactosidase-1-like protein 3) is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GLB1L3 polyclonal antibody detects endogenous levels of GLB1L3 protein.
Bioworld Molecular Weight: ~ 35 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of GLB1L3 polyclonal antibody at 1:500
Line1:Hela whole cell lysate
Line2:THP-1 whole cell lysate
Line3:H9C2 whole cell lysate
Line4:sp20 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human GLB1L3.
Conjugate: Unconjugated
Modification: Unmodified