Product Description

GLCNE Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46816-50, BS46816-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a bifunctional enzyme that initiates and regμlates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecμles is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecμles is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene resμlts in transcript variants encoding different isoforms. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: NM, DMRV, IBM2, Uae1, GLCNE

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human GLCNE

Dilution: WB: 1:1000-1:5000 ICC/IF: 1:50 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y223

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only