GLI2 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA32463-50, RA32463-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Background: GLI family zinc finger 2 (GLI2) Homo sapiens This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
Molecular Weight: 174
GeneID (Human): 2736
Protein MW (KDa): 174
SWISS: P10070
Source: Rabbit
Research Use Only