GLP-1R Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25342-50, RA25342-100
Citations, Manuals and MSDS Available upon request.
Background: glucagon like peptide 1 receptor (GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: GLP1R; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 2740
Protein MW (KDa): 53
SWISS: P43220
Source: Rabbit
Research Use Only