GLP1R Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21015-50, RA21015-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Alternative Names: Glucagon-like peptide 1 receptor (GLP-1 receptor) (GLP-1-R) (GLP-1R)
Background: glucagon like peptide 1 receptor (GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes inTerminalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 53
GeneID (Human): 2740
Protein MW (KDa): 53
SWISS: P43220
Source: Rabbit
Research Use Only