GLSK rabbit pAb - ES16173

GLSK rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES16173-50, ES16173-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human GLSK AA range: 162-212

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 2744

Human SWISS Prot NO: O94925

Subcellular Location: [Isoform 1]: Mitochondrion. Cytoplasm, cytosol. The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits.; [Isoform 3]: Mitochondrion.; [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix. Produced by the proteolytic processing of the 74-kDa cytosolic precursor.; [Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix. Produced by the proteolytic processing of the 74-kDa cytosolic precursor.

Research Use Only