Glucagon Monoclonal Antibody-MB66764

Glucagon Monoclonal Antibody

Catalogue Numbers: MB66764-50, MB66764-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P01275

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Glucagon is a pancreatic hormone that functions as an antagonist to Insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure.PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Glucagon protein.

Extra Notes: Western blot analysis of Glucagon expression in HepG2 (A), HT29 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Glucagon

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Glucagon. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified