Glucosidase IIα rabbit pAb - ES5316

Glucosidase IIα rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5316-50, ES5316-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016],

Alternate Name: GANAB; G2AN; KIAA0088; Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human GANAB. AA range:242-291

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 107kD

Human Gene ID: 23193

Human SWISS Prot NO: Q14697

Subcellular Location: Endoplasmic reticulum. Golgi apparatus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research Use Only