GluR-3 Monoclonal Antibody - BT-MCA0625

GluR-3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0625-50, BT-MCA0625-100

Citations, Manuals and MSDS Available upon request.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA-andgt;GGA| R-andgt;G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Research Areas: Signal transduction; Neuroscience

Target Protein: GRIA3

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Glutamate receptor 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P42263; Mouse: Q9Z2W9

Synonyms: GRIA3; GLUR3; GLURC; Glutamate receptor 3; GluR-3; AMPA-selective glutamate receptor 3; GluR-C; GluR-K3; Glutamate receptor ionotropic; AMPA 3; GluA3

GeneID: Human: 2892

Research Use Only