GLUR Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90580-50, BS90580-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P00390(Human) P70619(Rat)
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide (H2O2), a dangerously reactive species within the cell. In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms. The ratio of GSSG/GSH present in the cell is a key factor in properly maintaining the oxidative balance of the cell, that is, it is critical that the cell maintains high levels of the reduced glutathione and a low level of the oxidized Glutathione disulfide. This narrow balance is maintained by glutathione reductase, which catalyzes the reduction of GSSG to GSH.
Purification and Purity: Protein affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: GLUR polyclonal antibody detects endogenous levels of GLUR protein.
Bioworld Molecular Weight: 56 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of GLUR on different lysates using anti-GLUR antibody at 1/2,000 dilution.
Positive control:
Lane 1: A549
Lane 2: Rat liver tissue, ICC staining GLUR in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: GR, GRase, GSR, GLUR, GRD1, GLR1, GLUR, Glutathione reductase, Glutathione reductase mitochondrial, Glutathione reductase, mitochondrial, GR, Gr1, GRase, GRD 1, GRD1, GSHR, GSR, MGC78522,
Immunogen: Recombinant protein within human GLUR 260-450 aa.
Conjugate: Unconjugated
Modification: Unmodified