Product Description

GluR2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90581-50, BS90581-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P42262(Human) P23819(Mouse) P19491(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IF, IHC, IP,

All Applications: ICC:1:50-1:200
IHC:1:50-1:200
WB:1:500

Background: Lonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GluR2 polyclonal antibody detects endogenous levels of GluR2 protein.

Bioworld Molecular Weight: 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining GluR2 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining GluR2 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: GluR-2, GluA2, GRIA2, GLUR2, AMPA 2, AMPA selective glutamate receptor 2, AMPA-selective glutamate receptor 2, AMPA2, GluA2, GLUR 2, GLUR B, GluR K2, GluR-2, GluR-B, GluR-K2, GLUR2, GLURB, Glutamate receptor 2, Glutamate receptor ionotropic AMPA 2, Glutamate receptor ionotropic, Gria2, GRIA2, HBGR2,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified