Product Description

Glutamate receptor 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90585-50, BS90585-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P42261(Human) P23818(Mouse) P19490(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IP,

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200

Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Glutamate receptor 1 polyclonal antibody detects endogenous levels of Glutamate receptor 1 protein.

Bioworld Molecular Weight: 92 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GluR1 on rat brain lysates using anti-GluR1 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GluR1 antibody. Counter stained with hematoxylin.

Alternative Name: GluR-1, GluA1, , GLUR 1, GLUR A, AMPA 1, AMPA selective glutamate receptor 1, AMPA-selective glutamate receptor 1, GluA1, GLUH1, GluR K1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA, GluRK1, Glutamate receptor 1, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic, Glutamate receptor, ionotropic, AMPA 1, Gria1, GRIA1, HBGR1, MGC133252, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified