Glutaminase Monoclonal Antibody-MB10980

Glutaminase Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10980-50, MB10980-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O94925

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 73 kDa; Observed MW: 68 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Glutaminase in A549 using Glutaminase antibody, and DAPI., Western blot analysis of Glutaminase C in rat brain lysates using Glutaminase C antibody., Western blot analysis of Glutaminase in K562, 3T3, Hela lysates using Glutaminase antibody

Alternative Name: Glutaminase kidney isoform; GLS; GLS1; KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase

Immunogen: Recombinant protein of human Glutaminase C

Conjugate: Unconjugated

Modification: Unmodified