Product Description

Glutaminase Polyclonal Antibody

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17015-50, BZ17015-100

Swiss-Prot: O94925

Host: Rabbit

Glutaminase Polyclonal Antibody-BZ17015

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Background: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 73 kDa; Observed MW: 73,65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Glutaminase1/GLS1 in Jurkat, SKOV-3, HepG2Lysates using Glutaminase antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Glutaminase antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: Glutaminase kidney isoform; GLS; GLS1; KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase

Immunogen: A synthetic peptide of human Glutaminase

Modification: Unmodified

Conjugate: Unconjugated