GlyRβ Polyclonal Antibody - RA25381

GlyRβ Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25381-50, RA25381-100

Citations, Manuals and MSDS Available upon request.

Background: glycine receptor beta (GLRB) Homo sapiens This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2743

Protein MW (KDa): 56

SWISS: P48167

Source: Rabbit

Research Use Only