Product Description

GLYR1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71554-50, BS71554-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro. Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3. Promotes KDM1B demethylase activity. Stimμlates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac by EP300. Regμlates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regμlating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Putative oxidoreductase.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: GLYR1, BM045, HIBDL, N-PAC, NP60

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human GLYR1(NP_115958.2).

Dilution: WB, 1:500 - 1:2000 IHC, 1:100 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 60kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q49A26

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only