GM2/GD2 synthase rabbit pAb - ES2440

GM2/GD2 synthase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2440-50, ES2440-100

Citations, Manuals and MSDS Available upon request.

Background: beta-1, 4-N-acetyl-galactosaminyltransferase 1 (B4GALNT1) Homo sapiens GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G (M2) and G (D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G (M3) and G (D3) by a beta-1, 4 linkage, resulting in the synthesis of G (M2) and G (D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013],

Alternate Name: B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human B4GALNT1. AA range:281-330

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 2583

Human SWISS Prot NO: Q00973

Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein.

Research Use Only