GNA11 Polyclonal Antibody-BS77892

GNA11 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS77892-50, BS77892-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P29992

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF/ICC

All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:200

Background: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Extra Notes: Immunofluorescence analysis of NIH/3T3 cells using GNA11 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: GNA11; FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2

Immunogen: A synthetic peptide of human GNA11(NP_002058.2).

Conjugate: Unconjugated

Modification: Unmodified