GNA13 rabbit pAb - ES9699

GNA13 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9699-50, ES9699-100

Citations, Manuals and MSDS Available upon request.

Background: function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., PTM:Palmitoylation is critical for proper membrane localization and signaling., PTM:Phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha, beta and gamma, and inhibits Rho activation., similarity:Belongs to the G-alpha family. G (12) subfamily., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 41kD

Human Gene ID: 10672

Human SWISS Prot NO: Q14344

Subcellular Location: Cell membrane; Lipid-anchor. Melanosome. Cytoplasm. Nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Detected in the cytoplasm of Leydig cells and in the seminiferous epithelium, including differentiating cells from the spermatogonia to mature spermatozoa stages (PubMed:18703424). In round spermatids, also present in the nuclei (PubMed:18703424).

Research Use Only